It can destroy poops and fires like normal shots, however. Bob's Brain only explodes when hitting an enemy, and does not explode upon hitting a fire, poop, or wall.Bob's Brain is affected by most bomb modifiers.
Collecting three items from this set will transform Isaac into Bob. Once it explodes, it takes a few seconds to re-appear.This can make picking up the item a risky choice, as Bob's Brain will always fire, regardless of whether or not Isaac will be caught in the explosion.The explosion can hurt Isaac, dealing a full heart of damage.The poison damage is dealt 4 times, inflicting Isaac's Damage per tick. The poison deals double Isaac's Damage over time. If it hits an enemy, it deals 3.5 damage and explodes, further damaging and poisoning monsters.Bob's Brain is fired directly from where it is located in the chain of familiars behind Isaac, making aiming it slightly more difficult.Bob's Brain is fired directly from where Isaac is standing.Spawns a floating brain familiar that can be fired towards enemies as a projectile.